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control wt fibroblasts  (Greenwood Genetic Center)

 
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    Greenwood Genetic Center control wt fibroblasts
    Polyamine levels in wild-type (a: CMS-24949) and SMS mutant (b: CMS-26559, c: CMS-6233, and d: CMS-23916) <t>fibroblast</t> cell lines with or without treatment of Spm or prodrug 1 (5 μM) in the presence of AG (1 mM) after 72 h incubation at 37 °C. Values represent data from the experiment performed in triplicates ± SD, *p < 0.05, *** p < 0.001, **** p < 0.0001.
    Control Wt Fibroblasts, supplied by Greenwood Genetic Center, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/control+wt+fibroblasts/control+wt+fibroblasts/pmc09115777-652-20-10
    Average 90 stars, based on 1 article reviews
    control wt fibroblasts - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome"

    Article Title: Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome

    Journal: Journal of medicinal chemistry

    doi: 10.1021/acs.jmedchem.1c00419

    Polyamine levels in wild-type (a: CMS-24949) and SMS mutant (b: CMS-26559, c: CMS-6233, and d: CMS-23916) fibroblast cell lines with or without treatment of Spm or prodrug 1 (5 μM) in the presence of AG (1 mM) after 72 h incubation at 37 °C. Values represent data from the experiment performed in triplicates ± SD, *p < 0.05, *** p < 0.001, **** p < 0.0001.
    Figure Legend Snippet: Polyamine levels in wild-type (a: CMS-24949) and SMS mutant (b: CMS-26559, c: CMS-6233, and d: CMS-23916) fibroblast cell lines with or without treatment of Spm or prodrug 1 (5 μM) in the presence of AG (1 mM) after 72 h incubation at 37 °C. Values represent data from the experiment performed in triplicates ± SD, *p < 0.05, *** p < 0.001, **** p < 0.0001.

    Techniques Used: Mutagenesis, Incubation

    Polyamine levels in CMS-23916 (mutant) fibroblast cell lines untreated (UT) or treated with prodrug 1 (5 μM) only, NAC (2 mM) only, or a combination of prodrug 1 (5 μM) and NAC (2 mM). Values represent data from the experiment performed in triplicates ± S.D. *p < 0.05.
    Figure Legend Snippet: Polyamine levels in CMS-23916 (mutant) fibroblast cell lines untreated (UT) or treated with prodrug 1 (5 μM) only, NAC (2 mM) only, or a combination of prodrug 1 (5 μM) and NAC (2 mM). Values represent data from the experiment performed in triplicates ± S.D. *p < 0.05.

    Techniques Used: Mutagenesis

    Related Articles

    Control:

    Article Title: Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome
    Article Snippet: .. The authors wish to thank Dr. Charles Schwartz at the Greenwood Genetic Center for supplying the SRS cell lines and control wt fibroblasts and the Snyder Robinson Foundation for financial support of this work (UCF25068A04 to O.P.). ..



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    Image Search Results


    Polyamine levels in wild-type (a: CMS-24949) and SMS mutant (b: CMS-26559, c: CMS-6233, and d: CMS-23916) fibroblast cell lines with or without treatment of Spm or prodrug 1 (5 μM) in the presence of AG (1 mM) after 72 h incubation at 37 °C. Values represent data from the experiment performed in triplicates ± SD, *p < 0.05, *** p < 0.001, **** p < 0.0001.

    Journal: Journal of medicinal chemistry

    Article Title: Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome

    doi: 10.1021/acs.jmedchem.1c00419

    Figure Lengend Snippet: Polyamine levels in wild-type (a: CMS-24949) and SMS mutant (b: CMS-26559, c: CMS-6233, and d: CMS-23916) fibroblast cell lines with or without treatment of Spm or prodrug 1 (5 μM) in the presence of AG (1 mM) after 72 h incubation at 37 °C. Values represent data from the experiment performed in triplicates ± SD, *p < 0.05, *** p < 0.001, **** p < 0.0001.

    Article Snippet: The authors wish to thank Dr. Charles Schwartz at the Greenwood Genetic Center for supplying the SRS cell lines and control wt fibroblasts and the Snyder Robinson Foundation for financial support of this work (UCF25068A04 to O.P.).

    Techniques: Mutagenesis, Incubation

    Polyamine levels in CMS-23916 (mutant) fibroblast cell lines untreated (UT) or treated with prodrug 1 (5 μM) only, NAC (2 mM) only, or a combination of prodrug 1 (5 μM) and NAC (2 mM). Values represent data from the experiment performed in triplicates ± S.D. *p < 0.05.

    Journal: Journal of medicinal chemistry

    Article Title: Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome

    doi: 10.1021/acs.jmedchem.1c00419

    Figure Lengend Snippet: Polyamine levels in CMS-23916 (mutant) fibroblast cell lines untreated (UT) or treated with prodrug 1 (5 μM) only, NAC (2 mM) only, or a combination of prodrug 1 (5 μM) and NAC (2 mM). Values represent data from the experiment performed in triplicates ± S.D. *p < 0.05.

    Article Snippet: The authors wish to thank Dr. Charles Schwartz at the Greenwood Genetic Center for supplying the SRS cell lines and control wt fibroblasts and the Snyder Robinson Foundation for financial support of this work (UCF25068A04 to O.P.).

    Techniques: Mutagenesis